Immunoexpression of androgen receptor in genital tissues of male BALB/c mice

Aim: Androgens are hormones that essential for the differentiation and development of male genital organs, preserving their structural features maintaining functions. These exert effects on target tissues mainly through androgen receptors (AR). The aim this study was to determine AR immunoexpression pattern in mice. Materials Methods: A total 6 BALB/c mice were anesthetized with ether, tissues, which quickly removed from body, fixed Bouin’s solution 18 hours. Tissues underwent routine histological procedures after fixation embedded paraffin. Tissue sections cut a thickness 5 µm paraffin blocks taken slide examined by staining immunohistochemical methods. Results: AR-positive immunostaining testis observed only somatic cells such as Sertoli, peritubular myoid cells, Leydig cells. Germ AR-negative. In caput epididymis, ductus deferens, seminal vesicle, positive stromal especially epithelial Although some these them Conclusion: current study, it determined expression similar other species, although there minor differences. findings support hypothesis androgens fact androgens/ARs structures functions organs.